Carbapenem-idashobora kwihanganira IMP Kumenya K-Gushiraho (Impande Zitemba)
Kumenyekanisha ibicuruzwa
Carbapenem irwanya IMP Detection K-Set (Lateral Flow Assay) ni uburyo bwo gupima immunochromatografique bugamije kumenya neza karbapenemase yo mu bwoko bwa IMP muri koloni.Isuzuma ni laboratoire-ikoresha laboratoire ishobora gufasha mugupima imiterere ya IMP yo mu bwoko bwa karbapenem.
Ibiranga
| Izina | Carbapenem-idashobora kwihanganira IMP Kumenya K-Gushiraho (Impande Zitemba) |
| Uburyo | Uruhande rutemba |
| Ubwoko bw'icyitegererezo | Abakoloni |
| Ibisobanuro | Ibizamini 25 |
| Igihe cyo kumenya | 10-15 min |
| Ibintu byo gutahura | Carbapenem-irwanya Enterobacteriaceae (CRE) |
| Ubwoko bwo kumenya | IMP |
| Igihagararo | K-Set ihagaze neza mumyaka 2 kuri 2 ° C-30 ° C. |
Ibyiza
- Byihuta
Kubona ibisubizo muminota 15, iminsi 3 mbere yuburyo busanzwe bwo gutahura - Biroroshye
Byoroshye gukoresha, abakozi basanzwe ba laboratoire barashobora gukora badahuguwe - Nibyo
Ubukangurambaga bukabije kandi bwihariye
Umupaka muto wo gutahura: 0,20 ng / mL
Bashoboye kumenya byinshi muburyo busanzwe bwa IMP
- Igisubizo cyimbitse
Ntibikenewe kubara, ibisubizo byo gusoma biboneka - Ubukungu
Ibicuruzwa birashobora gutwarwa no kubikwa mubushyuhe bwicyumba, kugabanya ibiciro
Akamaro k'ikizamini cya CRE
Hamwe na hamwe, Enterobacterales nitsinda rikunze gutera indwara zitera indwara ziterwa n'ubuzima.Enterobacterales zimwe zishobora kubyara enzyme yitwa karbapenemase ituma antibiyotike nka karbapenem, penisiline, na cephalosporine idakora neza.Kubera iyo mpamvu, CRE yiswe "bacteri zijoro" kubera ko hari antibiyotike nkeya zindi, niba zihari, zisigaye zivura indwara ziterwa na mikorobe.
Indwara ya bacteri yo mu muryango wa Enterobacterales, harimo ubwoko bwa Klebsiella na Escherichia coli, irashobora gutanga karbapenemase.Carbapenemase ikorwa kenshi muri gen ziri mubintu byimurwa bishobora gukwirakwiza byoroshye kuva mikorobe kugeza mikorobe ndetse numuntu kumuntu.Nanone kubera gukoresha nabi antibiyotike nuburyo buke bwafashwe kugirango birinde gukwirakwira, ikibazo cya CRE cyiyongera cyane kigenda kibangamira ubuzima ku isi.
Mubisanzwe, gukwirakwiza CRE birashobora kugenzurwa na:
- Gukurikirana kwandura CRE
- Gutandukanya abarwayi bafite CRE
- Kuraho ibikoresho byubuvuzi bitera umubiri
- Witondere mugihe utanga antibiotike (cyane cyane karbapenem)
- Gukoresha tekinike isukuye kugirango ugabanye kwandura
- Kurikiza byimazeyo gahunda yo gukora laboratoire
……
Kumenya CRE bifite agaciro gakomeye mugukwirakwiza.Mugupima hakiri kare, abatanga ubuzima barashobora gutanga ubuvuzi bwumvikana kubarwayi bashobora kwandura CRE, bakanagera kubuyobozi bwibitaro.
Ubwoko bwa IMP karbapenemase
Carbapenemase bivuga ubwoko bwa β-lactamase ishobora nibura hydrolyze imipenem cyangwa meropenem, harimo A, B, D ubwoko butatu bwimisemburo yashyizwe mubikorwa bya molekile ya Ambler.Muri byo, Icyiciro B ni metallo-β-lactamase (MBLs), harimo karbapenemase nka IMP, VIM na NDM,.IMP yo mu bwoko bwa karbapenemase, izwi kandi nka imipenemase metallo-beta-lactamase itanga CRE, ni ubwoko busanzwe bwa MBLs bwaguzwe kandi buva mu cyiciro cya 3A.Irashobora hydrolyze hafi ya β-lactam antibiotique.
Igikorwa
- Ongeraho ibitonyanga 5 byicyitegererezo cyo kuvura
- Shira mikorobe ya bagiteri hamwe nu muti ushobora guterwa
- Shyiramo umugozi muri tube
- Ongeramo 50 μL kuri S neza, tegereza iminota 10-15
- Soma ibisubizo
Tegeka amakuru
| Icyitegererezo | Ibisobanuro | Kode y'ibicuruzwa |
| CPI-01 | Ibizamini 25 | CPI-01 |
