Aspergillus Galactomannan ELISA Igikoresho cyo Kumenya
Kumenyekanisha ibicuruzwa
FungiXpert® Aspergillus Galactomannan ELISA Detection Kit ni Enzyme ifitanye isano na immunosorbent ya Enzyme kugirango igaragaze neza antigen ya Aspergillus galactomannan antigen ya serumu ikuze n’abana bato hamwe na bronchoalveolar lavage (BAL).
Umubare w'indwara ziterwa na Aspergillose (IA) ku barwayi badafite ubudahangarwa uragenda wiyongera cyane kubera gukoresha antibiyotike.IA ifite umubare munini w'impfu ziterwa no kubura ibimenyetso bisanzwe byubuvuzi hamwe nuburyo bwiza bwo gusuzuma hakiri kare.Aspergillus fumigatus ni imwe mu ndwara ziterwa na virusi zitera indwara ya aspergillus ikabije ku barwayi barwaye immunosuppressive, igakurikirwa na Aspergillus flavus, Aspergillus niger na Aspergillus terreus.
Ibiranga
| Izina | Aspergillus Galactomannan ELISA Igikoresho cyo Kumenya |
| Uburyo | ELISA |
| Ubwoko bw'icyitegererezo | Serumu, amazi ya BAL |
| Ibisobanuro | 96 ibizamini / kit |
| Igihe cyo kumenya | 2 h |
| Ibintu byo gutahura | Aspergillus spp. |
| Igihagararo | Igikoresho gihamye kumwaka 1 kuri 2-8 ° C. |
| Umupaka muto | 0.5 ng / mL |
Amavu n'amavuko
Aspergillose itera (IA)
Ninde ushobora kwandura
Abarwayi bafite neutropenie igihe kirekire, nyuma yo guhindurwa cyangwa bafatanije nuburyo bukingira immunosuppressive.
Umubare munini
5% kugeza kuri 20%, ukurikije umubare w'abarwayi.
Umubare munini w'impfu
50% kugeza 80% bitewe niterambere ryihuta ryubwandu (ni ukuvuga ibyumweru 1-2 kuva ugitangira gupfa).
Biragoye gusuzuma
Biragoye kubona ibimenyetso bya histopathologie.Imyumvire yumuco iri hasi.≈30% by'imanza zikomeza kutamenyekana no kutavurwa iyo apfuye.
Ikizamini cya Galactomannan (GM)
- Antigen yihariye ya antigen iboneka murukuta rw'akagari irekurwa mugihe cyo gukura kwa aspergillose itera.
- Iminsi 7 kugeza 14 mbere yuko ibindi bimenyetso byo gusuzuma bigaragara.
Ihame
Ibyiza
- Iterambere ryinshi
Uburyo mpuzamahanga buyobora inzira yo kumenya, sensibilité yo hejuru kandi yihariye - Birenzeho
Hindura uburyo bwo gukora.Mugabanye ibyago byo kwanduza mugihe cyigeragezo - Byihuta
Kumenya intambwe imwe, kugabanya umubare wa incubation nigihe cyo gukaraba
- Ubukungu
Gabanya microplate, kuzigama ikiguzi - Ibyifuzo
Byasabwe nubuyobozi bwa IDSA kuri Aspergillose 2016 na ESCMID-ECMM-ERS umurongo ngenderwaho wa Aspergillose 2018
Ivuriro
Gusuzuma hakiri kare
- GM ni iminsi 5-8 mbere yibimenyetso byindwara ya aspergillose itera (IA);
- GM ni iminsi 7.2 mbere yikirenga CT scan;
- GM ni iminsi 12.5 mbere yo gutangira imiti igabanya ubukana bwa antifungal.
Gukurikirana neza
- GM ihwanye nubunini bwa fungus, ishobora kwerekana urugero rwanduye.
- Ibiri muri antigen ya GM byagabanutse hakoreshejwe imiti igabanya ubukana.
Ishingiro ryingenzi ryubuvuzi
- Mugabanye gukoresha imiti igabanya ubukana.
- Isano rikomeye hagati y'ibisubizo na GM ya kanseri ya hematologiya.
Kumenyekanisha hamwe ikizamini cya G na GM
- Umwihariko wo hejuru nagaciro keza ko guhanura
- Kumva neza
Tegeka amakuru
| Icyitegererezo | Ibisobanuro | Kode y'ibicuruzwa |
| GMKT-01 | 96 ibizamini / kit | FGM096-001 |
